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AAOIFI No. 21 screening

Is CBIO halal?

Crescent Biopharma, Inc.

Not halal

Crescent Biopharma, Inc. did not pass AAOIFI screening. The failed check is shown below.

Checked: 16 October 2026

Exchange

NASDAQ

Price

11.84

Day

-5.13%

Market cap

$449.8M

Industry

Biotechnology

Sector

Healthcare

What the company does

Crescent Biopharma (formerly GlycoMimetics) develops a bispecific cancer antibody (CR-001, blocking PD-1 and VEGF together), in clinical trials. No revenue; funded by investors.

What was checked

The AAOIFI standard has four steps: business activity first, then three financial ratios. Fail one and the stock is not halal.

  • Business activity

    No prohibited activity

  • Interest-bearing debt / market cap

    limit 30%

    Interest-bearing debt $0 ÷ 36-month average market cap $203.79M = 0.0%

    0.0%

    Pass

  • Cash & investments / market cap

    limit 30%

    Cash + interest-bearing securities $171.59M ÷ 36-month average market cap $203.79M = 84.2%

    84.2%

    Fail

  • Non-compliant income / total revenue

    limit 5%

    Interest income $2.88M ÷ annual revenue $10.84M (2025) = 26.5%

    26.5%

    Fail

Figures from the company's filings (2026-06-30), USD. Market cap is a 36-month average (the S&P Shariah index approach), so a one-day price move does not flip the verdict. Today's market cap: $449.85M.

For information (AAOIFI 3/1 note): cash + receivables are 93.9% of total assets (2026-06-30). AAOIFI recommends tangible assets of at least one third — this figure does not affect the verdict, and other major screeners do not apply it either.

In the lists

In the S&P 500
Not in the S&P 500

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This is neither investment advice nor a fatwa. Screening is based on public financial statements and AAOIFI standard No. 21; data may lag. For a personal decision consult your own scholar.

Earnings historyCBIO's next report date, EPS estimate vs actual for recent quarters and the post-earnings price move.View earnings →