Is SPRB halal?
Spruce Biosciences, Inc.
Not halal
Spruce Biosciences, Inc. did not pass AAOIFI screening. The failed check is shown below.
Checked: 13 October 2026
Exchange
NASDAQ
Price
39.65
Day
-4.39%
Market cap
$123.2M
Industry
Biotechnology
Sector
Healthcare
What the company does
Spruce Biosciences develops drugs for rare endocrine diseases; after ending its tildacerfont program its lead candidate is tralesinidase alfa (an enzyme for Sanfilippo syndrome type B). No commercial product or revenue; funded by investors.
What was checked
The AAOIFI standard has four steps: business activity first, then three financial ratios. Fail one and the stock is not halal.
Business activity
No prohibited activity
Interest-bearing debt / market cap
limit 30%
Interest-bearing debt $7.43M ÷ current market cap $123.21M = 6.0%
6.0%
Pass
Cash & investments / market cap
limit 30%
Cash + interest-bearing securities $96.30M ÷ current market cap $123.21M = 78.2%
78.2%
Fail
Non-compliant income / total revenue
limit 5%
—
No data
Figures from the company's filings (2026-06-30), USD. Market cap is a 36-month average (the S&P Shariah index approach), so a one-day price move does not flip the verdict.
In the lists
- In the S&P 500
- Not in the S&P 500
- Held by funds
- Not held by any tracked fund
Halal stocks in the same industry
The largest halal stocks in Biotechnology — for comparison.
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- Halal investingBlogWhy a company's cash affects whether its stock is halalLots of cash sounds like a good sign — but halal screening checks it separately. What counts, what doesn't, and where we are stricter than AAOIFI.
- Halal investingBlogAAOIFI Shariah Standard No. 21 in plain languageThe most widely used standard for halal stock screening: the two-step test, the three ratios and how it differs from other methods.
Halal is the first question. The second: when to enter?
Our scanner watches 1454 halal stocks around the clock and fires a signal with entry, TP and SL when a technical setup completes. The full signal history — with outcomes — is public.
This is neither investment advice nor a fatwa. Screening is based on public financial statements and AAOIFI standard No. 21; data may lag. For a personal decision consult your own scholar.